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Title: Commercial and Pre-Commercial Cell Detection Technologies for Defence against Bioterror 《商业化及半商业化生物恐怖细胞检测防卫技术》
Author: L.M Lechuga, F.P Milanovich, P. Skládal, O. Ignatov and T.R. Austin
ISBN: 978-1-58603-858-8
Price: 115
No. of pages: 180
Publisher: IOS press
Published: 2008/06
   



针对迅速崛起的生物恐怖带来的威胁,此书重点讨论了当今应对生物恐怖的相关商业化技术和设备,以及如何进一步发展新的生物传感器系统到商业应用,并探索BWA生物传感器中人为因素。除了讨论目前涌现的新的相关商用技术外,此书涵盖了现代技术系统和人类社会的相互关系,以及改善科学界和商业机构关系的尝试。有四个主要领域被提及:第一个领域是介绍最先进的生物传感器和生物检测系统,其或者已经面世,或者是非常接近商业化。典型的系统包括BIOHAWK ™ SASS 2000, RAPTOR, Bionas® 2500, OWLS,或便携式SPR。第二个领域是介绍了生物检测装置及系统的最新研究进展,包括DNA和蛋白质芯片,微米及纳米光学传感器,微传感器的CMOS芯片,电化学阵列,物理平台,电子光学检测,物质检测等。第三个领域是有将生物受体层技术应用到选择性检测BWA,如蛋白质印迹,分子印迹聚合物,膜工程( MIME ,细胞印迹,单克隆抗体,抗体合成和裂解噬菌体中等等的最新进展。最后一部分是讨论人的因素:和传感器发展相关的社会问题的发展和BWA检测技术的应用。

As a response to the rapidly emerging threat of bioterrorism, the objectives of this volume of Commercial and Pre-Commercial Cell Detection Technologies for Defence against Bioterror are to exchange information on commercially available technologies and equipment for defense against bioterrorism; to further the development of new biosensor system prototypes into a commercially available apparatus and to explore human factors in BWA biosensors. The new commercial and pre-commercial technologies that are currently emerging in the world are presented and explained. Furthermore, there is a discussion about the interaction of modern detection systems with society and a trial for improvement of the relation between the scientific community and commercial entities. There are four major areas highlighted: the first is a presentation of the most advanced biosensors and biodetection system which can be found in the market or are quite close to commercialization. Systems as the BIOHAWK™, SASS 2000, RAPTOR, Bionas® 2500, OWLS, or a portable SPR are presented in this section. The second issue is a presentation of the advances in the research of biodetection devices as DNA and protein microchips, micro and nanophotonic sensors, CMOS microsensor chips, electrochemical arrays, physical platforms, electro optical detection, mass detection, etc.

Then, there is a description of the latest developments in the employment of bioreceptor layers for the selective detection of BWA, as protein signatures, molecular imprinted polymers, membrane engineering (MIME), cell signatures, monoclonal antibodies, synthetic antibodies and lytic phages, among others. The last part is the discussion of the human factor: societal issues related to sensor development and employment for BWA detection.


【Highlight】

From Dynamics to Structure and Function of Model Bio-Molecular Systems 从动力学到结构学和生物分子模型系统的作用
Fundamentals of Verbal and Nonverbal Communication and the Biometric Issue 语言与非语言交流的基本原则与生物特征
Epigenetic Markers 渐生标识
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